Definition Clinically Significant Weight Loss

Unintentional weight loss - NHS Choices


...used to the change.  Counselling and support may be needed to help you get to this stage. Significant weight loss can also be the result of an  eating disorder , such as anorexia  or bulimia . If you think you have an eating disorder, talk to someone you trust and consider speaking to your GP. There are also several organisations you can talk to for information and advice, such as the eating disorders charit...


Weight Change - Clinical Methods - NCBI Bookshelf


...e increases tissue sodium-potassium adenosine triphosphatase (ATPase) activity resulting in an excess synthesis of ATPase and concomitant loss of heat energy. Thyroid hormone also increases beta-adrenergic receptor sensitivity to catecholamines. Since metabolic regulation is also under neural control, an activation of the sympathetic nervous system results in increased ...


Can You Lose Weight Without Exercise on a 1,000


... Lung and Blood Institute. Weight-Loss Calorie Needs Diets containing 1,000 calories a day are safe, effective weight-loss diets for inactive women who weigh less than 165 pounds, according to the National Heart, Lung and Blood Institute. Women weighing 165 pounds or more, active women and men need at least 1,200 calories daily to safely lose weight. Eating too few calories to lose weight can cause fatigue, headaches, dizziness, ...


Weight gain - definition of Weight gain by Medical dictionary


...distribution of weight in the waist region is a typical indicator of this type of obesity. It is associated with an increased risk of hypertension, diabetes, and other metabolic disorders. o·be·si·ty (ō-bē'si-tē) [MIM*601665] Excess of subcutaneous fat in proportion to lean body mass. Excess fat accumulation is associated with increase in size (hypertrophy) as wel...


Obesity and weight management in the elderly


...between ‘healthy diets’ for CHD prevention, and those for weight control. Certain diets will promote CHD, particularly through high saturated fat, salt and low fruit and vegetable consumption and these have not changed greatly in recent decades. The main dietary driver to obesity is a high-fat intake, with sugars also contributing for energy-dense foods and high-energy drinks. These issues tend to come together, since an energ...


Obesity - Cleveland Clinic Center for


...tive in carefully selected adolescent and older patients. Contraindications Patients who cannot tolerate general anesthesia because of cardiac, pulmonary, or hepatic insufficiency are not candidates for surgery. Additionally, patients must be able to understand the consequences of the surgery and comply with the extensive preoperative evaluation and postoperative lifestyle changes, diet, vitamin supplementation, and follow-up...


International Journal of Obesity - The definition of


...399. _link_/sj.ijo.0803175; published online 22 November 2005 The definition of weight maintenance J Stevens 1 , 2 , K P Truesdale 2 , J E McClain 1 and J Cai 3 1Department of Nutrition, School of Public Health, University of North Carolina, Chapel Hill, NC, USA 2Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC, ...


Definition of cancer cachexia : effect of weight loss


...a population that differed for self-reported functional aspects of quality of life. A weight loss ≥10% did, however, define a group of patients with different physician-reported performance scores and grip strengths. In marked contrast, a multifactor cachexia profile that was based on weight loss, food intake, and inflammatory status defined a cachectic population that had both a lower su...


Clinically significant and sustained weight


...obese women with polycystic ovary syndrome (PCOS) losing clinically significant amounts of weight during a standard follow-up by an endocrinologist. DESIGN: Reproductive Endocrinology Clinic of an academic center. PATIENT(S): Obese patients with PCOS assessed between May 2002 and September 2008. INTERVENTION(S): General nonstandardized advice on weight loss and exerci...


Involuntary Weight Loss - Special Subjects


...roxytryptophan, garcinia, guarana, guar gum, glucomannan, herbal diuretics, ma huang, pyruvate, St. John's wort, yerba mate Drugs of abuse Alcohol, amphetamines, cocaine, opioids In some disorders that cause involuntary weight loss, other symptoms tend to be more prominent, so that weight loss is usually not the chief complaint. Examples include the following: Some malabsorptive disorders: GI tract surgery and cystic fibrosis Chronic...


ACSM - ACSM in the News


...that  > 250 minutes/week of moderate-intensity physical activity will prevent weight re-gain. Energy/diet restriction combined with physical activity will increase weight loss as compared to diet alone. ACSM recommends that adults participate in at least 150 minutes/week of moderate-intensity physical activity to prevent significant weight gain and reduce associated chronic disease risk factors. ...


Involuntary Weight Loss and Protein - Energy Malnutrition


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Osteoporosis Information - Arthritis Information


...d on epidemiological data that link low bone mass with increased fracture risk. In study populations of Caucasian postmenopausal women, a bone mineral density that was lower than 2.5 standard deviations (SD) of normal peak bone mass was associated with a fracture prevalence of 50&037;, meaning that 50% of women with bone mass at this level had at least one bone fracture(ref 2). Based on these ...


Obesity : Practice Essentials, Background, Pathophysiology


...mance of an advertising campaign and may provide aggregate outcomes information to the advertiser. Advertising and Sponsored Programs: We may provide your Personal Information to third party sponsors of advertisements and Sponsored Programs. Specifically, when you are exposed to an advertisement through the Services, whether on a Site, in a newsletter or through som...


Appropriate Physical Activity Intervention Strategies for


...e training on weight loss maintenance in obese, middle-aged men: a randomized trial. Int J Obes Relat Metab Disord. 2002;26:676-83. Boudou P, Sobngwi E, Mauvais-Jarvis F, Vexiau P, Gautier JF. Absence of exercise-induced variations in adiponectin levels despite decreased abdominal adiposity and improved insulin sensitivity in type 2 diabetic men. Eur J Endocr...


Obesity Treatment and Management : Approach Considerations


...ons from the sponsor. We also collect Non-Personal Information about your use of Sponsored Programs through cookies and web beacons, as described below. Market Research: From time to time, we may invite you to participate in market research surveys for WebMD and market research surveys conducted on behalf of third party sponsors either by WebMD or a third party ("Sponsored Su...


What Is the Definition of Clinically Significant


...icance, or the mathematical determination of an event, symptom, behavior, etc. not occurring merely by chance. While some statistically significant events may not be clinically relevant, clinically significant events may sometimes be statistically significant. This is how clinical significance plays out in practice. Clinicians use up-to-date research to inform their treatment and clinical judgment. A treatment that's research might ...


Aerobic exercise alone results in clinically significant


...anges were significantly different compared with the control group that declined −2.8 ± 5.6%. The change in maximal oxygen consumption was not significantly different between the exercise groups and was not significantly different between men and women for the 400 and 600 kcal/session groups and control group. Energy intake/physical activity There were no significant b...


Aerobic exercise alone results in clinically significant


...ies in individuals where exercise was verified, prescribed exercise by level of EEEx, and delivered in a dose sufficient to induce weight loss. For example, Ross et al. 29 reported a mean weight loss of 8% in 16 obese middle age men (~45 yrs.) who completed 700 kcal/day (70% peak VO2) treadmill exercise over 12 weeks. Ross et al. 30 have shown similar results in a samp...


SURG.00024 Bariatric Surgery and Other Treatments for


...able Gastric Band), vertical banded gastroplasty, biliopancreatic bypass with duodenal switch, and sleeve gastrectomy (open or laparoscopic) are considered investigational and not medically necessary when the above criteria are not met. Gastric bypass, using a Billroth II type of anastomosis (also known as a "mini gastric bypass") is considered investigational and not...


Get The Facts On Eating Disorders - National Eating


...2003). Review of the prevalence and incidence of eating disorders. International Journal of Eating Disorders, 34(4), 383-396. Hudson J. I., Hiripi E., Pope H. G. Jr., & Kessler R. C. (2007). The prevalence and correlates of eating disorders in the National Comorbidity Survey Replication.Biological Psychiatry, 61, 348-358. Mangweth, B., Hudson, J. I., Pope, H. G. Jr., Hausmagn, A., DeCol, C....


Physical Activity, Weight Loss and Weight Regain


...estigators introduce an energy deficit of 700 to 1000 kilocalories per day, 'diet only' and 'diet plus exercise' result in similar losses. Donnelly explains that this is due to metabolic adaptations that “diminish any additive effect of energy expenditure from physical activity on weight loss”. However, in investigations where the energy deficit is 500-700 kilocalories/day, the 'diet plus exercise' group is about 2...


Effectiveness of the MOVE! Multidisciplinary Weight Loss


... tailored to individual needs based on medical history, weight and weight management history, motivational factors, barriers to modifying physical activity, diet and weight-related behavior, and veterans’ readiness to change these behaviors. Staff assisted the patient with setting 1 to 3 specific short-term nutrition, physical activity, or behavior-change goals and supported the veteran weekly for...


Weight loss - unintentional : MedlinePlus Medical Encyclopedia


...swelling or infection in the pancreas Removal of part of the small intestine Overuse of laxatives Eating disorders, anorexia nervosa that have not been diagnosed yet Diabetes that have not been diagnosed Overactive thyroid gland Home Care Your health care provider may suggest changes in your diet and an exercise program depending on the cause of your weight loss. When to Contact a Medical Professional Call your h...


What is Obesity? - Health News


...sumption of sweetened drinks has contributed significantly to the raised carbohydrate intake of most young American adults over the last three decades. The consumption of fast-foods has tripled over the same period. Various other factors are also said to have contributed to America's increased calorie and carbohydrate intake: In 1984 the Reagan administration freed up advertis...


Appropriate Physical Activity Intervention Strategies for


...een amended to include the text additions. Abstract Overweight and obesity affects more than 66% of the adult population and is associated with a variety of chronic diseases. Weight reduction reduces health risks associated with chronic diseases and is therefore encouraged by major health agencies. Guidelines of the National Heart, Lung, and Blood Institute (...


Weight loss - Wikipedia, the free encyclopedia


...racteristics Unintentional weight loss may result from loss of body fats, loss of body fluids, muscle atrophy, or even a combination of these. [1] [2] It is generally regarded as a medical problem when at least 10% of a person's body weight has been lost in six months [1] [3] or 5% in the last month. [4] Another criterion used for assessing weight that is too ...


Statistical significance - Institute for Work and Health


...ur weight loss study. If the results yield a p-value of .05, here is what the scientists are saying: "Assuming the two groups of people being compared were exactly the same from the start, there's a very good chance — 95 per cent — that the three-kg difference in weight loss would NOT be observed if the weight loss drug had no benefit whatsoever." From this finding, scientists would infer that the weight l...


Starvation nursing home severe weight loss - Hamill Law


...ters:: "Avoidable/Unavoidable" failure to maintain acceptable parameters of nutritional status: "Avoidable" means that the resident did not maintain acceptable parameters of nutritional status and that the facility did not do one or more of the following: evaluate the resident's clinical condition and nutritional risk factors; define and implement interventions that are consiste...


Clinical significance - Wikipedia, the free encyclopedia


...ance as “the extent to which therapy moves someone outside the range of the dysfunctional population or within the range of the functional population.” [10] They proposed two components of this index of change: the status of a patient or client after therapy has been completed, and “how much change has occurred during the course of therapy.” [10] Clinical significance is also a consideration when interpreting the resul...